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I.V. Glutathione for integrative cancer treatment

Glutathione, also known as “the master antioxidant,” is a powerful substance produced and used by all cells in the body. Glutathione has a broad repertoire of clinically proven benefits for health.

However, its levels can be compromised during disease, and cancer is, perhaps, the most glutathione-depleting disease there is.

Glutathione deficiencies are common in patients with long-term diseases or exposed to high levels of oxidative stress by toxic substances. [1]

What is glutathione?

Glutathione is a peptide composed of three important amino acids, hence it is also called tripeptide. [1]

Researchers have suggested that cellular levels of glutathione could be used as a biomarker to determine life expectancy. [1, 2]

Glutathione is the most important antioxidant in the body. What makes glutathione unique is that it is found inside each of the cells in our body. Without glutathione, our cells cannot carry out their activities optimally. [1]

Glutathione does much more than simply inhibit free radicals. It also protects many systems and organs during disease or the deterioration that a disease entails.

Glutathione has been defined as a “defense agent against toxicity by xenobiotics” — that is, it protects against the harm of taking drugs, environmental pollutants and carcinogens. [1]

A deficiency of glutathione can manifest itself in the form of increased susceptibility to oxidative stress, which is thought to be involved in the genesis of a wide variety of diseases, such as Alzheimer's, Parkinson's and also cancer. [1]

The regulation of glutathione metabolism “could be a fundamental part in any strategy to provide health.” [1, 2]

Hence, glutathione deficiencies can lead to the onset of several diseases or the worsening of already present ones. There are several ways to increase its levels in the body, i. e. through the oral intake of it or nutraceuticals that are precursors of it like alpha lipoic acid, NAC, etc.

A powerful way of delivering glutathione to all tissues in your body is by I.V. infusion, a safe and efficient procedure when applied by a well-trained health expert.

How glutathione is beneficial for cancer patients

It is the most potent antioxidant. Oxidative stress is one of the contributing factors to the development of cancers. [3] Glutathione reduces the number of reactive oxygen species (ROS) and the damage caused by oxidative stress in cells and DNA. [1, 2, 4] Glutathione protects against chronic diseases linked to oxidative stress. Oxidative stress has been related to diseases from cancer to neurodegeneration, among others.In addition to neutralizing reactive oxygen species (ROS), glutathione has the incredible ability to “regenerate” other antioxidantsProtects cells from damage caused by free radicals (unstable molecules made by the process of oxidation during normal metabolism). Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. Antioxidants include beta-carotene, lycopene, Vitamins A, C, and E, and other natural and manufactured substances. in the body such as vitamin C and Vitamin E. [1]

It fights inflammation. A chronic inflammatory status of our body is a contributing factor to the development or worsening of cancer. [3] Glutathione is known to inhibit the production of most inflammatory cytokines. [1] Glutathione deficiency causes inflammation of the airways in mice. This inflammation was reduced and completely restored once glutathione was started. [1]
Glutathione inhibits the transcription factor NF-K, which increases several genes related to inflammation. [1]

It is an essential part of an integrative treatment for cancer. Glutathione is the most important actor in the regulation of life, proliferation, and death of cancer cells. Glutathione deficiency leads to an increase in oxidative stress damage that facilitates cancer progression. There is a correlation between the increase in glutathione intake and the decrease in the risk of mouth and throat cancer. [1]

Glutathione is also key in the repair of damage caused to cells and tissues by chemotherapy drugs in cancer patients (1). Glutathione is essential in the elimination and detoxification of carcinogenic substances. However, very high levels of glutathione, being an antioxidant, could reduce the effectiveness of certain chemotherapy drugs. So it is necessary to maintain a certain balance. That is, increase the levels without overdosing in case of chemotherapy. [1, 2]

At Verita Life, Glutathione forms just one part of our integrative cancer treatment program.

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  1. Pompella A1, Visvikis A, Paolicchi A, De Tata V, Casini AF. The changing faces of glutathione, a cellular protagonist. Biochem Pharmacol. 2003 Oct 15;66(8):1499-503.
  2. Cascella R1, Evangelisti E1, Zampagni M1, Becatti M1, D’Adamio G2, Goti A2, Liguri G1, Fiorillo C1, Cecchi C3. S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans. Free Radic Biol Med. 2014 Aug;73:127-35. doi: 10.1016/j.freeradbiomed.2014.05.004. Epub 2014 May 15.
  3. Gabriele Multhoff, Michael Molls, and Jürgen Radons. Chronic Inflammation in Cancer Development. Front Immunol. 2011; 2: 98. Published online 2012 Jan 12. doi: 10.3389/fimmu.2011.00098. PMCID: PMC3342348. PMID: 22566887.
  4. Perricone C1, De Carolis C, Perricone R. Glutathione: a key player in autoimmunity. Autoimmun Rev. 2009 Jul;8(8):697-701. doi: 10.1016/j.autrev.2009.02.020. Epub 2009 Feb 13.

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